Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Angiotensin II provokes podocyte injury in murine model of HIV-associated nephropathy.

American journal of physiology. Renal physiology - 1 Oct 2007

Ideura Hiroshi, Hiromura Keiju, Hiramatsu Noriyuki, Shigehara Tetsuya, Takeuchi Shigeru, Tomioka Mai, Sakairi Toru, Yamashita Shin, Maeshima Akito, Kaneko Yoriaki, Kuroiwa Takashi, Kopp Jeffrey B, Nojima Yoshihisa

Abstract excerpt

Conditional transgenic mice that express one of the human immunodeficiency virus (HIV)-1 accessory genes, vpr, selectively in podocytes using a podocin promoter and a tetracycline-inducible system develop renal injuries similar to those of patients with HIV-associated nephropathy (HIVAN). We have shown that a heminephrectomy accelerates podocyte injury, which is alleviated by angiotensin II (ANG II) type 1...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Angiotensin II
Share to Angiotensin II Type 1 Receptor Blockers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antihypertensive Agents

Share to Blood Pressure

Share to Gene Products, vpr

Share to Norepinephrine

Share to Podocytes

Share to Receptor, Angiotensin, Type 1

Source

Identifiers

PMID: 17652372
DOI: 10.1152/ajprenal.00162.2007

Genes

ANG

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Angiotensin II provokes podocyte injury in murine model of HIV-associated nephropathy.PMID 17652372Read ↗

HIV-1 Genes vpr and nef Synergistically Damage Podocytes, Leading to GlomerulosclerosisSemantic proximity Read ↗

Fluvastatin prevents podocyte injury in a murine model of HIV-associated nephropathy.Semantic proximity Read ↗

Adverse host factors exacerbate occult HIV-associated nephropathy.Semantic proximity Read ↗

Modulation of renin angiotensin system predominantly alters sclerotic phenotype of glomeruli in HIVAN.Semantic proximity Read ↗

Transgenic and Infectious Animal Models of HIV-Associated NephropathySemantic proximity Read ↗

Expression of HIV-1 genes in podocytes alone can lead to the full spectrum of HIV-1-associated nephropathy.Semantic proximity Read ↗

APOL1-G0 protects podocytes in a mouse model of HIV-associated nephropathy.Semantic proximity Read ↗

<i>APOL1-G0</i> protects podocytes in a mouse model of HIV-associated nephropathySemantic proximity Read ↗

The molecular pathogenesis of HIV-1 associated nephropathy: recent advances.Semantic proximity Read ↗

Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression.Semantic proximity Read ↗

Diabetic kidney disease in FVB/NJ Akita mice: temporal pattern of kidney injury and urinary nephrin excretion.Semantic proximity Read ↗

Dysregulation of podocyte phenotype in idiopathic collapsing glomerulopathy and HIV-associated nephropathy.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.