Article

<i>APOL1-G0</i> protects podocytes in a mouse model of HIV-associated nephropathy

2019-04-05

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> African polymorphisms in the gene for Apolipoprotein L1 ( APOL1 ) confer a survival advantage against lethal trypanosomiasis but also an increased risk for several chronic kidney diseases (CKD) including HIV-associated nephropathy (HIVAN). APOL1 is expressed in renal cells, however, the pathogenic events that lead to renal cell damage and kidney disease are not fully unders...

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Literature Corpus work: dd795009-1674-5e5a-b9fe-12fa39d32e32
DOI: 10.1101/598557

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