Article
Nephropathy in human immunodeficiency virus-1 transgenic mice is due to renal transgene expression.
1 Jul 1997
Abstract excerpt
HIV-associated nephropathy (HIVAN) is a progressive glomerular and tubular disease that is increasingly common in AIDS patients and one of the leading causes of end stage renal disease in African Americans. A major unresolved issue in the pathogenesis of HIVAN is whether the kidney disease is due to renal cell infection or a "bystander" phenomenon mediated by systemically dysregulated cytokines. To address this...
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