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Article

The molecular pathogenesis of HIV-1 associated nephropathy: recent advances.

Journal of molecular medicine (Berlin, Germany) - 1 May 2011

Papeta Natalia, Sterken Roel, Kiryluk Krzysztof, Kalyesubula Robert, Gharavi Ali G

Abstract excerpt

HIV-1-associated nephropathy (HIVAN) is a major complication of HIV-1 infection, frequently resulting in kidney failure. HIVAN arises due to HIV-1-induced dysregulation of podocytes, the glomerular epithelial cells that establish and maintain the kidney filtration barrier. Host genetic factors are important for the development of HIVAN. The risk of HIVAN is greatest in populations of African ancestry, and is...

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PMID: 21221512
DOI: 10.1007/s00109-010-0719-x

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APOL1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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