Article
Fluvastatin prevents podocyte injury in a murine model of HIV-associated nephropathy.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Aug 2009
Sakurai Noriyuki, Kuroiwa Takashi, Ikeuchi Hidekazu, Hiramatsu Noriyuki, Takeuchi Shigeru, Tomioka Mai, Shigehara Tetsuya, Maeshima Akito, Kaneko Yoriaki, Hiromura Keiju, Kopp Jeffery B, Nojima Yoshihisa
Abstract excerpt
BACKGROUND: Recent studies have reported that statins have renoprotective effects, independent from lowering plasma cholesterol. In this study, we examined whether statins were beneficial in a murine model of HIV-associated nephropathy (HIVAN). METHODS: We used conditional transgenic mice that ex...
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