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Article

Transgenic and Infectious Animal Models of HIV-Associated Nephropathy

4 Jun 2009

Abstract excerpt

HIV-associated nephropathy (HIVAN) is a major cause of HIV-related morbidity and mortality. Transgenic and infectious models of HIVAN faithfully recapitulate the human disease and are important tools in advancing our understanding of disease pathogenesis, genetic susceptibility, and therapeutic intervention beyond the inhibition of viral replication. This review discusses the available transgenic murine models...

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PMID: 19497967
DOI: 10.1681/asn.2008121230

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