Article
Decreased peak bone mass is associated with a 3-bp deletion/insertion of the CYP19 intron 4 polymorphism: preliminary data from the GOOS study.
Journal of endocrinological investigation - 1 Jun 2007
Kastelan D, Grubic Z, Kraljevic I, Duric K, Kardum I, Dusek T, Stingl K, Giljevic Z, Kerhin-Brkljacic V, Suchanek E, Korsic M
Abstract excerpt
Finding that estrogen plays an important role in bone homeostasis in men prompted research on relationship of polymorphism at the CYP19 gene and the bone mass. Therefore, influence of 3-bp deletion/insertion polymorphism of CYP19 (TTTA)7 allele on the peak bone mass attainment in males was studied. Fifty-eight unrelated male participants, aged 21-35, were selected depending on the presence of (TTTA)7 (no.=19) or...
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