Article
Age-related influence of common aromatase gene polymorphisms on bone mass of healthy men.
Bone - 1 Jul 2004
Zarrabeitia Ana, Zarrabeitia María T, Valero Carmen, González-Macías Jesús, Riancho José A
Abstract excerpt
Androgens and estrogens are critical factors for bone homeostasis; hence, polymorphisms of genes involved in the metabolism and activity of sex steroids are likely candidates to influence bone mass. Therefore, we studied the association of two of those microsatellite polymorphisms, situated in intron 4 of CYP19-aromatase and exon 1 of androgen receptor, with bone mass in a group of 324 healthy men of a wide age...
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