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Article

Differential activation of polymorphisms of the formyl peptide receptor by formyl peptides.

Biochimica et biophysica acta - 1 Sept 2007

Mills John S

Abstract excerpt

We have investigated the role of two polymorphic sites (R190W and N192K) on the binding and activation of the formyl peptide receptor (FPR) by viral and formyl peptides. WEDWVGWI, a peptide with antiviral activity derived from the membrane proximal region of feline immunodeficiency virus, binds with high affinity to FPR. The three tryptophans in the peptide are all essential for FPR binding, just as they were...

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Identifiers

PMID: 17644322
DOI: 10.1016/j.bbadis.2007.06.001
PMCID: PMC2094211

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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