Article
Species and subtype variants of the N-formyl peptide chemotactic receptor reveal multiple important functional domains.
The Journal of biological chemistry - 5 Dec 1993
Gao J L, Murphy P M
Abstract excerpt
The N-formyl peptide receptor (FPR) is a seven transmembrane-domain receptor that mediates trafficking and activation of phagocytic leukocytes in response to N-formyl oligopeptides such as fMet-Leu-Phe. cDNAs for high affinity FPRs have been cloned from both human (huFPR) and rabbit (rabFPR). To...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Cloning, Molecular
- DNA Primers
- Genetic Variation
- Humans
- Kinetics
- Mice
- Models, Structural
- Molecular Sequence Data
- N-Formylmethionine Leucyl-Phenylalanine
- Neutrophils
- Oligonucleotides, Antisense
- Oocytes
- Polymerase Chain Reaction
- Protein Conformation
- Protein Structure, Secondary