Article
A novel gene trapping for identifying genes expressed under the control of specific transcription factors.
Biochemical and biophysical research communications - 14 Sept 2007
Naruse Chie, Fukusumi Yoshiyasu, Kakiuchi Dai, Asano Masahide
Abstract excerpt
Gene trapping is a powerful method for identifying novel genes and for analyzing their functions. It is, however, difficult to select trapped genes on the basis of their function. To identify genes regulated by transcription factors that are important in the mesodermal formation, we selected trapped ES clones by infection of adenoviral vectors expressing Pax1, Brachyury, and Foxa2. Among 366 trapped genes, seven...
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