Article
[Generation of Ayu17-449 gene knockout mice by gene trapping].
Yi chuan = Hereditas - 1 Feb 2006
Tang Hua, Tang Ren-Kuan, Huang Ai-Long, Araki Kimi, Yamamura Kenichi
Abstract excerpt
We report the generation of Ayu17-449 gene knockout mice in an effort to facilitate studies of its function during mouse development, A special gene trapping vector was transfected into mouse ES cells. The clone with the trapped gene trap was identified by 5' RACE and Southern blot analysis. Ayu17-449 trapped mice were then generated by using this ES clone. In addition, the expression of Ayu17-449 in this mutant...
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