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Article

A novel view of the transcriptome revealed from gene trapping in mouse embryonic stem cells.

Genome research - 1 Jul 2007

Roma Guglielmo, Cobellis Gilda, Claudiani Pamela, Maione Francesco, Cruz Pedro, Tripoli Gaetano, Sardiello Marco, Peluso Ivana, Stupka Elia

Abstract excerpt

Embryonic stem (ES) cells are pluripotent cell lines with the capacity of self-renewal and the ability to differentiate into specific cell types. We performed the first genome-wide analysis of the mouse ES cell transcriptome using approximately 250,000 gene trap sequence tags deposited in public databases. We unveiled >8000 novel transcripts, mostly non-coding, and >1000 novel alternative and often...

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Source

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Identifiers

PMID: 17540781
DOI: 10.1101/gr.5720807
PMCID: PMC1899116

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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