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Article

Efficiency assessment of the gene trap approach.

Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jun 1998

Voss A K, Thomas T, Gruss P

Abstract excerpt

The trapping of genes in murine embryonic stem (ES) cells offers three features in one experimental approach: 1) analysis of the expression patterns of unknown genes by using a simple staining method, 2) rapid cloning of unknown genes, and 3) generation of mutant mouse lines. We performed a gene trap screen aimed at the discovery of new genes regulating embryonic development. We have processed 209 gene trap...

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PMID: 9626493
DOI: 10.1002/(SICI)1097-0177(199806)212:2<171::AID-AJA3>3.0.CO;2-E

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Source receipt: pubmed, retrieved 7 Sept 2026.

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