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Article

Gene trap: a way to identify novel genes and unravel their biological function.

FEBS letters - 25 Aug 2000

Cecconi F, Meyer B I

Abstract excerpt

The gene trap methodology is a powerful tool to characterize novel genes and analyze their importance in biological phenomena. It is based on the use of mouse embryonic stem cells and reporter vectors designed to randomly integrate into the genome, tagging an insertion site and generating a mutation. Theoretically, all the 100,000 genes present in the mouse genome could be tagged and functionally inactivated at...

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PMID: 10967330
DOI: 10.1016/s0014-5793(00)01779-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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