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Article

Effective gene trapping mediated by Sleeping Beauty transposon.

PloS one - 1 Jan 2012

Song Guili, Li Qing, Long Yong, Gu Qilin, Hackett Perry B, Cui Zongbin

Abstract excerpt

Gene trapping is a high-throughput approach to elucidate gene functions by disrupting and recapitulating expression of genes in a target genome. A number of transposon-based gene-trapping systems are developed for mutagenesis in cells and model organisms, but there is still much room for the improvement of their efficiency in gene disruption and mutation. Herein, a gene-trapping system mediated by Sleeping Beauty...

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Identifiers

PMID: 22952894
DOI: 10.1371/journal.pone.0044123
PMCID: PMC3432063

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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