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Article

Mutant non-coding RNA resource in mouse embryonic stem cells.

Disease models & mechanisms - 5 Feb 2021

Hansen Jens, von Melchner Harald, Wurst Wolfgang

Abstract excerpt

Gene trapping is a high-throughput approach that has been used to introduce insertional mutations into the genome of mouse embryonic stem (ES) cells. It is performed with generic gene trap vectors that simultaneously mutate and report the expression of the endogenous gene at the site of insertion and provide a DNA sequence tag for the rapid identification of the disrupted gene. Large-scale international efforts...

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Identifiers

PMID: 33729986
DOI: 10.1242/dmm.047803
PMCID: PMC7875499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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