Article
High-resolution fluorescent analysis of microsatellite instability in gastric cancer.
European journal of gastroenterology & hepatology - 1 Aug 2007
Sakurai Masato, Zhao Yan, Oki Eiji, Kakeji Yoshihiro, Oda Shinya, Maehara Yoshihiko
Abstract excerpt
BACKGROUND: Microsatellite instability (MSI) is associated with various human malignancies and regarded as reflecting cellular deficiency in DNA mismatch repair (MMR). Analysis of MSI has been prevalent in the field of oncology, and numerous data have accumulated in the literature. It has been reported that the MSI+ phenotype is relatively frequent in gastric cancer. The reported frequencies of MSI+ gastric...
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