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Article

Genetic instability in human mismatch repair deficient cancers.

Annales de genetique - 1 Jan 2000

Duval Alex, Hamelin Richard

Abstract excerpt

Cancers showing microsatellite instability (MSI-H) are frequent tumors characterized by inactivating alterations of mismatch repair (MMR) genes that lead to an incapacity to recognize and repair errors that occur during DNA replication. These cancers can be inherited as in the human non-polyposis colorectal cancer syndrome, or can occur sporadically in 10-15% of colorectal, gastric and endometrial cancers. MSI-H...

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Identifiers

PMID: 12119215
DOI: 10.1016/s0003-3995(02)01115-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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