Article
Low-frequency microsatellite instability in genomic di-nucleotide sequences correlates with lymphatic invasion and poor prognosis in gastric cancer.
Cell biochemistry and biophysics - 1 Jan 2015
Zhao Yan, Zheng Zhi-Chao, Luo Ya-Hong, Piao Hao-Zhe, Zheng Guo-Liang, Shi Jing-Yi, Zhang Tao, Zhang Jian-Jun
Abstract excerpt
The clinical significance of low-frequency microsatellite instability (MSI-L) in gastric cancer (GC) has not been well established. The aim of this study was to evaluate the clinicopathological features of MSI-L in GC. We investigated microsatellite instability (MSI) in 5 di-nucleotide repeat sequences in 210 unselected GC patients. High-resolution fluorescent microsatellite analysis assay was utilized to detect...
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