Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Development of a fluorescent multiplex assay for detection of MSI-High tumors.

Disease markers - 1 Jan 2004

Bacher Jeffery W, Flanagan Laura A, Smalley Regenia L, Nassif Nadine A, Burgart Lawrence J, Halberg Richard B, Megid Wael M Abdel, Thibodeau Stephen N

Abstract excerpt

Determining whether a tumor exhibits microsatellite instability (MSI) is useful in identifying patients with hereditary non-polyposis colorectal cancer and sporadic gastrointestinal cancers with defective DNA mismatch repair (MMR). The assessment of MSI status aids in establishing a clinical prognosis and may be predictive of tumor response to chemotherapy. A reference panel of five markers was suggested for MSI...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Neoplasms
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Fluorescent Dyes

Share to Gastrointestinal Neoplasms

Share to Immunohistochemistry

Share to Microscopy, Fluorescence

Share to Oligonucleotides

Share to Sensitivity and Specificity

Source

Open in PubMed Open full text

Identifiers

PMID: 15528789
DOI: 10.1155/2004/136734
PMCID: PMC3839403

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Development of a fluorescent multiplex assay for detection of MSI-High tumors.PMID 15528789Read ↗

Detection of microsatellite instability in colorectal cancer using an alternative multiplex assay of quasi-monomorphic mononucleotide markers.Semantic proximity Read ↗

Use of mononucleotide repeat markers for detection of microsatellite instability in mouse tumorsSemantic proximity Read ↗

High-resolution fluorescent analysis of microsatellite instability in gastric cancer.Semantic proximity Read ↗

Detection of microsatellite instability by fluorescence multiplex polymerase chain reaction.Semantic proximity Read ↗

MSI-testing in hereditary non-polyposis colorectal carcinoma (HNPCC).Semantic proximity Read ↗

Mononucleotide repeats BAT-26 and BAT-25 accurately detect MSI-H tumors and predict tumor content: implications for population screening.Semantic proximity Read ↗

Improved Detection of Microsatellite Instability in Early Colorectal Lesions.Semantic proximity Read ↗

DNA Mismatch Repair Deficiency Detection in Colorectal Cancer by a New Microsatellite Instability Analysis System.Semantic proximity Read ↗

Quality assessment and correlation of microsatellite instability and immunohistochemical markers among population- and clinic-based colorectal tumors results from the Colon Cancer Family Registry.Semantic proximity Read ↗

Tumor-specific microsatellite instability: do distinct mechanisms underlie the MSI-L and EMAST phenotypes?Semantic proximity Read ↗

Validation of Long Mononucleotide Repeat Markers for Detection of Microsatellite InstabilitySemantic proximity Read ↗

High throughput detection of microsatellite instability by denaturing high-performance liquid chromatography.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.