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Article

Precise assessment of microsatellite instability using high resolution fluorescent microsatellite analysis

1 Sept 1997

Abstract excerpt

The instability of microsatellite sequences dispersed in the genome has been linked to a deficiency in cellular mismatch repair. This phenotype has been frequently observed in various human neoplasms and is regarded as a major factor in tumorigenesis. To demonstrate alterations in microsatellite sequences, polymerase chain reaction (PCR) and electrophoretic analysis are techniques often used. However, the...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Identifiers

PMID: 9254697
DOI: 10.1093/nar/25.17.3415

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Source receipt: pubmed, retrieved 7 Sept 2026.

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