Article
Function of recQ family helicase in genome stability.
Sub-cellular biochemistry - 1 Jan 2006
Seki Masayuki, Tada Shusuke, Enomoto Takemi
Abstract excerpt
The recQ gene of Escherichia coli is the founding member of the RecQ family of helicases. Like E. coli, lower eukaryotic species also possess single RecQ proteins, such as Sgs1 and Rqh1 in budding and fission yeast, respectively. However, there are five RecQ helicases in human as well as in chicken cells. Three of the human RecQ helicases are encoded by BLM, WRN and RECQL4 genes, defects of which give rise to the...
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