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Article

Functional relation among RecQ family helicases RecQL1, RecQL5, and BLM in cell growth and sister chromatid exchange formation.

Molecular and cellular biology - 1 May 2003

Wang Wensheng, Seki Masayuki, Narita Yoshiyasu, Nakagawa Takayuki, Yoshimura Akari, Otsuki Makoto, Kawabe Yoh-ichi, Tada Shusuke, Yagi Hideki, Ishii Yutaka, Enomoto Takemi

Abstract excerpt

Human RECQL1 and RECQL5 belong to the RecQ family that includes Bloom syndrome, Werner syndrome, and Rothmund-Thomson syndrome causative genes. Cells derived from individuals suffering from these syndromes show significant levels of genomic instability. However, neither RECQL1 nor RECQL5 has been related to a disease, and nothing is known about the functions of RecQL1 and RecQL5. We generated here RECQL1(-/-),...

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Identifiers

PMID: 12724411
DOI: 10.1128/MCB.23.10.3527-3535.2003
PMCID: PMC164753

Genes

BLM
RECQL5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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