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Human RecQ Helicases in DNA Double-Strand Break Repair

25 Feb 2021

Abstract excerpt

RecQ DNA helicases are a conserved protein family found in bacteria, fungus, plants, and animals. These helicases play important roles in multiple cellular functions, including DNA replication, transcription, DNA repair, and telomere maintenance. Humans have five RecQ helicases: RECQL1, Bloom syndrome protein (BLM), Werner syndrome helicase (WRN), RECQL4, and RECQL5. Defects in BLM and WRN cause autosomal...

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PMID: 33718381
DOI: 10.3389/fcell.2021.640755

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