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Article

RECQ DNA helicases and osteosarcoma.

Advances in experimental medicine and biology - 1 Jan 2014

Lu Linchao, Jin Weidong, Liu Hao, Wang Lisa L

Abstract excerpt

The RECQ family of DNA helicases is a conserved group of enzymes that are important for maintaining genomic integrity. In humans, there are five RECQ helicase genes, and mutations in three of them-BLM, WRN, and RECQL4-are associated with the genetic disorders Bloom syndrome, Werner syndrome, and Rothmund-Thomson syndrome (RTS), respectively. Importantly all three diseases are cancer predisposition syndromes....

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Topics

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Share to Bone and Bones
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Neoplastic

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Source

Identifiers

PMID: 24924172
DOI: 10.1007/978-3-319-04843-7_7

Genes

RECQL4
BLM
WRN

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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