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Article

Mutations in conserved functional domains of human RecQ helicases are associated with diseases and cancer: A review.

Biophysical chemistry - 1 Oct 2020

Mojumdar Aditya

Abstract excerpt

RecQ helicases belong to a ubiquitous family of DNA unwinding enzymes that are essential to maintain genome stability by acting at the interface between DNA replication, recombination, and repair. Humans have five different paralogues of RecQ helicases namely RecQ1, BLM, WRN, RecQ4, and RecQ5. Germ-line mutations in these helicases give rise to distinct human genetic disorders, Bloom Syndrome, Werner Syndrome,...

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Identifiers

PMID: 32702531
DOI: 10.1016/j.bpc.2020.106433

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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