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Article

Molecular genetics of RecQ helicase disorders.

Cellular and molecular life sciences : CMLS - 1 Sept 2007

Hanada K, Hickson I D

Abstract excerpt

The RecQ helicases belong to the Superfamily II group of DNA helicases, and are defined by amino acid motifs that show sequence similarity to the catalytic domain of Escherichia coli RecQ. RecQ helicases have crucial roles in the maintenance of genome stability. In humans, there are five RecQ helicases and deficiencies in three of them cause genetic disorders characterised by cancer predisposition, premature...

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Identifiers

PMID: 17571213
DOI: 10.1007/s00018-007-7121-z
PMCID: PMC11136437

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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