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Article

Variants with different mutation patterns persist in the quasispecies of enfuvirtide-resistant HIV-1 population during and after treatment in vivo.

Journal of acquired immune deficiency syndromes (1999) - 1 Oct 2007

Trabaud Mary Anne, Cotte Laurent, Labernardière Jean Louis, Lebel-Binay Sophie, Icard Vinca, Tardy Jean-Claude, Trepo Christian, Andre Patrice

Abstract excerpt

BACKGROUND: Genotypic and phenotypic resistance in 11 HIV-1-infected patients receiving enfuvirtide (ENF), as part of a salvage regimen, has been evaluated. METHODS: Resistance mutations were detected by sequencing the gp41 ectodomain from plasma samples. During treatment, longitudinal samples from 1 patient were sequenced after limiting dilution of complementary DNA to isolate single genomes. Phenotypic...

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Source

Identifiers

PMID: 17621239
DOI: 10.1097/QAI.0b013e3181354710

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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