Article
Genotypic analysis of the gp41 HR1 region from HIV-1 isolates from enfuvirtide-treated and untreated patients.
Journal of acquired immune deficiency syndromes (1999) - 1 Aug 2011
Pessoa Luciana Santos, Valadão Ana Luiza Chaves, Abreu Celina Monteiro, Calazans Alexandre Rodrigues, Martins Angélica Nascimento, Azevedo Suwellen S S D, Couto-Fernandez José Carlos, Azevedo Marcelo C M V, Tanuri Amilcar
Abstract excerpt
OBJECTIVE: To evaluate the polymorphisms and resistance mutations in gp41 HR1 region of HIV-1. METHODS: The study included 28 HIV-positive patients undergoing enfuvirtide (ENF) treatment or not from Porto Alegre, Rio Grande do Sul state, and Rio de Janeiro, Rio de Janeiro state, between 2006 and 2009. Resistance mutations and polymorphisms of the gp41 HR1 region were detected using the genomic DNA of 12...
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