Article
Primary resistance to enfuvirtide (T20) in recently HIV-1 infected, antiretroviral-naive patients from the ANRS Aquitaine Cohort.
Antiviral therapy - 1 Jan 2007
Peuchant Olivia, Capdepont Sophie, Ragnaud Jean-Marie, Aurillac-Lavignolle Valérie, Thiébaut Rodolphe, Fleury Hervé, Masquelier Bernard
Abstract excerpt
BACKGROUND: Transmission of HIV-1 variants with resistance to reverse transcriptase (RT) and protease inhibitors has been widely characterized in developed countries. However, no clear evidence of primary resistance to HIV-1 fusion inhibitors has been shown so far. We wished to investigate the possibility of genotypic resistance to enfuvirtide (T20) in a cohort of antiretroviral-naive, recently infected patients....
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