Article
Natural variability in the HR-1 and HR-2 domains of HIV type 1 gp41 from different clades circulating in Italy.
AIDS research and human retroviruses - 1 Apr 2007
Razzolini Francesca, Vicenti Ilaria, Saladini Francesco, Micheli Valeria, Romano Laura, Cargnel Antonietta, Zazzi Maurizio
Abstract excerpt
The human immunodeficiency virus type 1 (HIV-1) HR-1 and HR-2 gp41 regions were sequenced in a total of 228 plasma or peripheral blood mononuclear cell samples obtained from an equal number of enfuvirtide-naive subjects for pol genotypic resistance testing in clinical practice. Phylogenetic analysis of the env sequences indicated that 102 belonged to subtype B and 95 to non-B subtypes (31 CRF02_AG, 21 F1, 14 C,...
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