Article
HIV-1 gp41 genetic diversity and enfuvirtide resistance-associated mutations among enfuvirtide-naïve patients in southern China.
Virus research - 15 Jan 2021
Chang Le, Zhao Junpeng, Guo Fei, Ji Huimin, Zhang Lu, Jiang Xinyi, Wang Lunan
Abstract excerpt
BACKGROUND: Human immunodeficiency virus (HIV) increasing molecular diversity and emergence of drug resistant mutants remain a major concern in China. Enfuvirtide (ENF/T-20) is the first entry inhibitor used in patients failing highly active antiretroviral therapy (HAART). However, data on HIV-1 gp41genetic diversity and primary ENF resistance-associated mutations among treatment-naïve patients in China is...
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