Article
Genotype and phenotype patterns of human immunodeficiency virus type 1 resistance to enfuvirtide during long-term treatment.
Antimicrobial agents and chemotherapy - 1 Sept 2004
Menzo Stefano, Castagna Antonella, Monachetti Alessia, Hasson Hamid, Danise Anna, Carini Elisabetta, Bagnarelli Patrizia, Lazzarin Adriano, Clementi Massimo
Abstract excerpt
The human immunodeficiency virus type 1 (HIV-1) fusion inhibitor enfuvirtide has recently been introduced into clinical practice and has exhibited efficient anti-HIV-1 activity in combination with other antiretroviral agents. In the present study, we addressed the effect of long-term treatment with enfuvirtide on the intrahost evolution of HIV-1. The genotype and phenotype patterns and the relative replication...
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