Article
ATP depletion inhibits the endocytosis of ClC-2.
Journal of cellular physiology - 1 Jan 2008
Dhani Sonja U, Kim Chiaw Patrick, Huan Ling-Jun, Bear Christine E
Abstract excerpt
The chloride channel, ClC-2 is expressed ubiquitously and participates in multiple physiological processes. In particular, ClC-2 has been implicated in the regulation of neuronal chloride ion homeostasis and mutations in ClC-2 are associated with idiopathic generalized epilepsy. Despite the physiological and pathophysiological significance of this channel, its regulation remains incompletely understood. The...
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