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Article

A Novel View on the Role of Intracellular Tails in Surface Delivery of the Potassium-Chloride Cotransporter KCC2.

eNeuro - 1 Jan 2000

Friedel Perrine, Ludwig Anastasia, Pellegrino Christophe, Agez Morgane, Jawhari Anass, Rivera Claudio, Medina Igor

Abstract excerpt

A plethora of neurological disorders are associated with alterations in the expression and localization of potassium-chloride cotransporter type 2 (KCC2), making KCC2 a critical player in neuronal function and an attractive target for therapeutic treatment. The activity of KCC2 is determined primarily by the rates of its surface insertion and internalization. Currently the domains of KCC2 dictating its...

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Identifiers

PMID: 28785725
DOI: 10.1523/ENEURO.0055-17.2017
PMCID: PMC5520751

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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A Novel View on the Role of Intracellular Tails in Surface Delivery of the Potassium-Chloride Cotransporter KCC2.PMID 28785725Read ↗

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