Article
Cytoplasmic ATP-sensing domains regulate gating of skeletal muscle ClC-1 chloride channels.
The Journal of biological chemistry - 16 Sept 2005
Bennetts Brett, Rychkov Grigori Y, Ng Hooi-Ling, Morton Craig J, Stapleton David, Parker Michael W, Cromer Brett A
Abstract excerpt
ClC proteins are a family of chloride channels and transporters that are found in a wide variety of prokaryotic and eukaryotic cell types. The mammalian voltage-gated chloride channel ClC-1 is important for controlling the electrical excitability of skeletal muscle. Reduced excitability of muscle cells during metabolic stress can protect cells from metabolic exhaustion and is thought to be a major factor in...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.