Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inhibiting endoplasmic reticulum (ER)-associated degradation of misfolded Yor1p does not permit ER export despite the presence of a diacidic sorting signal.

Molecular biology of the cell - 1 Sept 2007

Pagant Silvere, Kung Leslie, Dorrington Mariana, Lee Marcus C S, Miller Elizabeth A

Abstract excerpt

Capture of newly synthesized proteins into endoplasmic reticulum (ER)-derived coat protomer type II (COPII) vesicles represents a critical juncture in the quality control of protein biogenesis within the secretory pathway. The yeast ATP-binding cassette transporter Yor1p is a pleiotropic drug pump that shows homology to the human cystic fibrosis transmembrane conductance regulator (CFTR). Deletion of a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COP-Coated Vesicles
Share to Endoplasmic Reticulum

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HSP40 Heat-Shock Proteins

Share to Molecular Chaperones

Share to Mutant Proteins

Share to Protein Processing, Post-Translational

Share to Protein Sorting Signals

Share to Ubiquitin-Conjugating Enzymes

Source

Open in PubMed Open full text

Identifiers

PMID: 17615300
DOI: 10.1091/mbc.e07-01-0046
PMCID: PMC1951769

Genes

CFTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inhibiting endoplasmic reticulum (ER)-associated degradation of misfolded Yor1p does not permit ER export despite the presence of a diacidic sorting signal.PMID 17615300Read ↗

Folding Status Is Determinant over Traffic-Competence in Defining CFTR Interactors in the Endoplasmic ReticulumSemantic proximity Read ↗

Interplay of substrate retention and export signals in endoplasmic reticulum quality control.Semantic proximity Read ↗

ER-golgi traffic is a prerequisite for efficient ER degradation.Semantic proximity Read ↗

Evolving questions and paradigm shifts in endoplasmic-reticulum-associated degradation (ERAD).Semantic proximity Read ↗

Functional rescue of a misfolded eukaryotic ATP-binding cassette transporter by domain replacement.Semantic proximity Read ↗

Dfm1 promotes Ste24-dependent translocon quality controlSemantic proximity Read ↗

COPII-dependent export of cystic fibrosis transmembrane conductance regulator from the ER uses a di-acidic exit code.Semantic proximity Read ↗

Pbn1p: an essential endoplasmic reticulum membrane protein required for protein processing in the endoplasmic reticulum of budding yeast.Semantic proximity Read ↗

An acidic sequence of a putative yeast Golgi membrane protein binds COPII and facilitates ER export.Semantic proximity Read ↗

Structure and function of the ER-Membrane ComplexSemantic proximity Read ↗

Yos9p and Hrd1p mediate ER retention of misfolded proteins for ER-associated degradation.Semantic proximity Read ↗

Multiple degradation pathways for misfolded mutants of the yeast plasma membrane ATPase, Pma1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.