Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Pbn1p: an essential endoplasmic reticulum membrane protein required for protein processing in the endoplasmic reticulum of budding yeast.

Proceedings of the National Academy of Sciences of the United States of America - 24 Jan 2006

Subramanian Shoba, Woolford Carol A, Drill Emily, Lu Meng, Jones Elizabeth W

Abstract excerpt

PBN1 was identified as a gene required for production of protease B (PrB) activity in Saccharomyces cerevisiae. PBN1 encodes an endoplasmic reticulum (ER)-localized, type I membrane glycoprotein and is essential for cell viability. To study the essential function(s) of Pbn1p, we constructed a strain with PBN1 under control of the GAL promoter. Depletion of Pbn1p in this strain abrogates processing of the ER...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Calnexin
Share to Cathepsin A

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Galactose

Share to Genome, Fungal

Share to Molecular Chaperones

Share to Oxidoreductases Acting on Sulfur Group Donors

Share to Protein Denaturation

Share to Serine Endopeptidases

Source

Open in PubMed Open full text

Identifiers

PMID: 16418276
DOI: 10.1073/pnas.0505570103
PMCID: PMC1347969

Genes

GAL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Pbn1p: an essential endoplasmic reticulum membrane protein required for protein processing in the endoplasmic reticulum of budding yeast.PMID 16418276Read ↗

PNG1, a yeast gene encoding a highly conserved peptide:N-glycanase.Semantic proximity Read ↗

ER-golgi traffic is a prerequisite for efficient ER degradation.Semantic proximity Read ↗

Eps1, a novel PDI-related protein involved in ER quality control in yeast.Semantic proximity Read ↗

Stress tolerance of misfolded carboxypeptidase Y requires maintenance of protein trafficking and degradative pathways.Semantic proximity Read ↗

Identification and assessment of the role of a nominal phospholipid binding region of ORP1S (oxysterol-binding-protein-related protein 1 short) in the regulation of vesicular transport.Semantic proximity Read ↗

Functional characterization of the fission yeast phosphatidylserine synthase gene, pps1, reveals novel cellular functions for phosphatidylserine.Semantic proximity Read ↗

Orm1 and Orm2 are conserved endoplasmic reticulum membrane proteins regulating lipid homeostasis and protein quality control.Semantic proximity Read ↗

A dominant negative mutant of PMA1 interferes with the folding of the wild type enzyme.Semantic proximity Read ↗

ER-associated degradation relying on protein O-mannosylationSemantic proximity Read ↗

Over-expression of S. cerevisiae G1 cyclins restores the viability of alg1 N-glycosylation mutants.Semantic proximity Read ↗

The medial-Golgi ion pump Pmr1 supplies the yeast secretory pathway with Ca2+ and Mn2+ required for glycosylation, sorting, and endoplasmic reticulum-associated protein degradation.Semantic proximity Read ↗

Inhibiting endoplasmic reticulum (ER)-associated degradation of misfolded Yor1p does not permit ER export despite the presence of a diacidic sorting signal.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.