Article
An acidic sequence of a putative yeast Golgi membrane protein binds COPII and facilitates ER export.
The EMBO journal - 3 Dec 2001
Votsmeier C, Gallwitz D
Abstract excerpt
We previously identified Sys1p as a high copy number suppressor of Ypt6 GTPase-deficient yeast mutants that are defective in endosome-to-Golgi transport. Here, we show that Sys1p is an integral membrane protein that resides on a post-endoplasmic reticulum (ER) organelle(s). Affinity studies with detergent- solubilized yeast proteins showed that the C-terminal 53 amino acid tail of Sys1p binds effectively to the...
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