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Article

Unique developmental trajectories and genetic regulation of ventricular and outflow tract progenitors in the zebrafish second heart field

23 Oct 2017

Abstract excerpt

During mammalian embryogenesis, cardiac progenitor cells constituting the second heart field (SHF) give rise to the right ventricle and primitive outflow tract (OFT). In zebrafish, previous lineage-tracing and mutant analyses suggested that SHF ventricular and OFT progenitors co-migrate to the arterial pole of the zebrafish heart tube soon after their specification in the nkx2.5+ field of anterior lateral plate...

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PMID: 29061637
DOI: 10.1242/dev.153411

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