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Article

Structural determinates for apolipoprotein E-derived peptide interaction with the alpha7 nicotinic acetylcholine receptor.

Molecular pharmacology - 1 Oct 2007

Gay Elaine A, Bienstock Rachelle J, Lamb Patricia W, Yakel Jerrel L

Abstract excerpt

Neuronal nicotinic acetylcholine receptor (nAChR) signaling has been implicated in a variety of normal central nervous system (CNS) functions as well as an array of neuropathologies. Previous studies have demonstrated both neurotoxic and neuroprotective actions of peptides derived from apolipoprotein E (apoE). It has been discovered that apoE-derived peptides inhibit native and recombinant alpha7-containing...

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Source

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Identifiers

PMID: 17609418
DOI: 10.1124/mol.107.035527
PMCID: PMC2742887

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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