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Therapeutic Potential of α7 Nicotinic Acetylcholine Receptors.

Pharmacological reviews - 1 Oct 2015

Bertrand Daniel, Lee Chih-Hung L, Flood Dorothy, Marger Fabrice, Donnelly-Roberts Diana

Abstract excerpt

Progress in the fields of neuroscience and molecular biology has identified the forebrain cholinergic system as being important in many higher order brain functions. Further analysis of the genes encoding the nicotinic acetylcholine receptors (nAChRs) has highlighted, in particular, the role of α7 nAChRs in these higher order brain functions as evidenced by their peculiar physiologic and pharmacological...

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PMID: 26419447
DOI: 10.1124/pr.113.008581

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