Article
Neuronal nicotinic acetylcholine receptors: from the gene to the disease.
Behavioural brain research - 1 Aug 2000
Weiland S, Bertrand D, Leonard S
Abstract excerpt
The neuronal nicotinic acetylcholine receptors are excitatory ligand-gated channels. Widely expressed throughout the peripheral and central nervous system, their properties depend upon their subunit composition. Furthermore, genetic studies have revealed a high degree of variation at the genomic level and alternative splicing of the mRNAs coding for these integral membrane proteins. In particular, genes coding...
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