Article
Reporter gene insertions reveal a strictly B lymphoid-specific expression pattern of Pax5 in support of its B cell identity function.
Journal of immunology (Baltimore, Md. : 1950) - 15 Jun 2007
Fuxa Martin, Busslinger Meinrad
Abstract excerpt
The transcription factor Pax5 is essential for B cell commitment and development. Although the detail Pax5 expression pattern within the hemopoietic system is still largely unknown, we previously reported that Pax5 is monoallelically transcribed in pro-B and mature B cells. In this study, we have...
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