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Article

Biphenotypic B-lymphoid/myeloid cells expressing low levels of Pax5: potential targets of BAL development.

Blood - 1 Nov 2012

Simmons Szandor, Knoll Marko, Drewell Christopher, Wolf Ingrid, Mollenkopf Hans-Joachim, Bouquet Corinne, Melchers Fritz

Abstract excerpt

The expression of Pax5 commits common lymphoid progenitor cells to B-lymphoid lineage differentiation. Little is known of possible variations in the levels of Pax5 expression and their influences on hematopoietic development. We have developed a retroviral transduction system that allows for the study of possible intermediate stages of this commitment by controlling the levels of Pax5 expressed in Pax5-deficient...

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Share to B-Lymphocytes
Share to Cell Lineage

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Immunoblotting

Share to Myeloid Cells

Share to PAX5 Transcription Factor

Share to Precursor Cell Lymphoblastic Leukemia-Lymphoma

Share to Precursor Cells, B-Lymphoid

Share to Transduction, Genetic

Source

Identifiers

PMID: 22927250
DOI: 10.1182/blood-2012-03-414821

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