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Article

Novel processing of Notch 1 within its intracellular domain by a cysteine protease.

Neuro-degenerative diseases - 1 Jan 2007

Fassa Angeliki, Parisiadou Loukia, Robakis Nikolaos K, Efthimiopoulos Spiros

Abstract excerpt

In order to study N1 processing, we expressed human N1 (hN1) in HEK293 cells (293-hN1). Following Western blot analysis of 293-hN1 extracts, we detected, in addition to full-length hN1 and the N1 extracellular domain truncated form (N1-TM), a novel extracellular domain truncated form of hN1 with...

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Identifiers

PMID: 17596709
DOI: 10.1159/000101839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17596709-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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