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Article

Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter.

Nature - 1 Jan 1991

Powis S J, Townsend A R, Deverson E V, Bastin J, Butcher G W, Howard J C

Abstract excerpt

In mammalian cells, short peptides derived from intracellular proteins are displayed on the cell membrane associated with class I molecules of the major histocompatibility complex (MHC). The surface presentation of class I-peptide complexes presumably alerts the immune system to intracellular viral protein synthesis. Peptides derived from the cytosol must reach the cisternae of the endoplasmic reticulum where...

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PMID: 1758495
DOI: 10.1038/354528a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Restoration of antigen presentation to the mutant cell line RMA-S by an MHC-linked transporter.PMID 1758495Read ↗

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Tumorigenicity conferred to lymphoma mutant by major histocompatibility complex-encoded transporter gene.Semantic proximity Read ↗

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Increased class Ib antigen display on TAP-2 mutant cells by a mitochondrial function inhibitor.Semantic proximity Read ↗

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