Article
An endogenous antigenic peptide bypasses the class I antigen presentation defect in RMA-S.
The Journal of experimental medicine - 1 Mar 1992
Hosken N A, Bevan M J
Abstract excerpt
The RMA-S cell line was derived from the Raucher virus-induced murine cell line RBL-5 by ethylmethane sulfonate mutagenesis and anti-H-2 antibody plus complement selection (Ljunggren, H.-G., and K. Karre. 1985. J. Exp. Med. 162:1745). RMA-S is defective in the ability to present endogenously synthesized antigens to class I major histocompatibility complex (MHC)-restricted cytotoxic T lymphocytes (CTL) (Townsend,...
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