An endogenous antigenic peptide bypasses the class I antigen presentation defect in RMA-S.

doi:10.1084/jem.175.3.719

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Article

An endogenous antigenic peptide bypasses the class I antigen presentation defect in RMA-S.

The Journal of experimental medicine - 1 Mar 1992

Hosken N A, Bevan M J

Abstract excerpt

The RMA-S cell line was derived from the Raucher virus-induced murine cell line RBL-5 by ethylmethane sulfonate mutagenesis and anti-H-2 antibody plus complement selection (Ljunggren, H.-G., and K. Karre. 1985. J. Exp. Med. 162:1745). RMA-S is defective in the ability to present endogenously synthesized antigens to class I major histocompatibility complex (MHC)-restricted cytotoxic T lymphocytes (CTL) (Townsend,...

Topics

Animals
Antigen-Presenting Cells
Antigens, Neoplasm
Antigens, Viral
Cell Fusion
Cell Line
Chromatography, High Pressure Liquid
Chromosome Mapping
Chromosomes, Human, Pair 17
Cytotoxicity, Immunologic
Female

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Histocompatibility Antigens Class I

Humans

Mice

Mice, Inbred AKR

Mice, Inbred C57BL

Nucleoproteins

Orthomyxoviridae

Source

Open in PubMed Open full text

Identifiers

PMID: 1311017
DOI: 10.1084/jem.175.3.719
PMCID: PMC2119158

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1311017-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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