Article
Citrus auraptene suppresses azoxymethane-induced colonic preneoplastic lesions in C57BL/KsJ-db/db mice.
Nutrition and cancer - 1 Jan 2007
Hayashi Kei, Suzuki Rikako, Miyamoto Shingo, Shin-Ichiroh Yoshitani, Kohno Hiroyuki, Sugie Shigeyuki, Takashima Shigeki, Tanaka Takuji
Abstract excerpt
The current study was designed to investigate whether dietary citrus auraptene (AUR) suppresses the development of azoxymethane (AOM)-induced colorectal preneoplastic lesions in C57BL/KsJ-db/db (db/db) mice with obese and diabetic phenotypes. Female db/db and wild (+/+) mice were divided into the AOM + AUR, AOM alone, AUR alone, and the untreated groups in each phenotype. AOM was given 3 weekly intraperitoneal...
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